Progress 64 West^SM is a civic organization established to promote the responsible growth of commerce in the greater St. Louis region, with a particular emphasis given to the I-64 corridor from I-270 westward to I-70.

The organization recognizes that the establishment and growth of commerce is essential to the community's viability by providing jobs for its residents and a tax base for high-quality public education systems and other necessary public services and amenities.

Progress 64 West^SM has not-for-profit and tax exempt status under Section 501(c)4 of the United States Internal Revenue Code.